Current view on the diagnosis and treatment of neuromyelitis optica spectrum disorders exacerbations
نویسندگان
چکیده
Irreversible neurological deficit and disability in neuromyelitis optica spectrum disorders (NOSD) are formed as a result of exacerbations, which often life-threatening. Timely diagnosis treatment exacerbations is key task the management this category patients. A unified structured approach to NOSD has not been developed. The purpose article analyze scientific literature data on issue order optimize diagnostics everyday clinical practice.
منابع مشابه
Neuromyelitis Optica Spectrum Disorders: Diagnosis and Treatment
The last decade has witnessed rapid developments in the clinical understanding and scienti fi c foundati on of neuromyeliti s opti ca (NMO). The landmark events were the late 19th century report by Devic and Gault describing the associati on of severe acute transverse myeliti s and opti c neuriti s and the late 20th century discovery that the syndrome was associated with a specifi c autoanti bo...
متن کاملTreatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate
BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...
متن کاملCurrent concept of neuromyelitis optica (NMO) and NMO spectrum disorders.
Neuromyelitis optica (NMO) has been described as a disease clinically characterised by severe optic neuritis (ON) and transverse myelitis (TM). Other features of NMO include female preponderance, longitudinally extensive spinal cord lesions (>3 vertebral segments), and absence of oligoclonal IgG bands . In spite of these differences from multiple sclerosis (MS), the relationship between NMO and...
متن کاملO 14: Differentiating Demyelinating Disorders of the Central Nervous System – a Focus on Multiple Sclerosis and Neuromyelitis-Optica Spectrum Disorders
Significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. The most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. During the last ten years, this view was subsequently changed and the term neuromyelitis ...
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ژورنال
عنوان ژورنال: Nevrologiâ, nejropsihiatriâ, psihosomatika
سال: 2022
ISSN: ['2310-1342', '2074-2711']
DOI: https://doi.org/10.14412/2074-2711-2022-5-69-76